I've had probably 5 nights in a row now of nightmares. There's nothing special going on - no more stress than there has been, no more earth-shattering, life-changing events, and yet I'm having nightmare after nightmare after nightmare. They're very similar to the nightmares I've had when weaning off antidepressants in the past.
I haven't looked too hard, but I recall being told that all psychoactive drugs, including SSRIs, must be fat-soluble to pass into the brain. Treating metabolic syndrome (including insulin resistance) can improve depression and bipolar symptoms. SSRIs can cause weight gain.
....and if you stop taking them, and start losing weight, you can have pockets of the medication stashed away in those fat cells, which then re-enter the brain, even though you've technically weaned off the drug.
Not that my scale says I've lost weight, but some of my pants seem a bit looser.
Couple that with the return of severe intestinal symptoms, seemingly tied to my metformin, and one might get the impression that I'm finally getting enough exercise to improve things, though it's hard to say for sure.
It seems that I slept crooked on my wrist Sunday night. Wrist and elbow are vaguely achy, and carrying anything very heavy with that hand is uncomfortable. I really ought to dig up my brace from back when I screwed up my wrist good.
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